Estimated global and regional economic burden of genital herpes simplex virus infection among 15–49 year-olds in 2016

Table 1 Economic burden of HSV by regions

WHO region	All countries	High-income countries	Upper-middle income countries	Low-middle income countries	Low-income countries
	GUD due to HSV-2 (I$ million)
Global	30,807	9589	13,586	6612	1020
African	3354	0.7	1367	1182	804
Americas	6486	4160	2221	91	14
Eastern Mediterranean	1749	131	735	734	149
Europe	4040	2297	1498	235	10
South-East Asia^b	3879	-	438	3398	43
Western Pacific^c	11,299	3001	7327	971	-
	GUD due to HSV-1 (I$ million)
Global	3988	2219	1501	238	30
African^a	-	-	-	-	-
Americas	1956	1443	488	21	4
Eastern Mediterranean	194	32	65	74	23
Europe	902	599	254	45	4
South-East Asia^b	16	-	0.8	15	0.2
Western Pacific^c	920	145	693	83	-
	Neonatal herpes due to a maternal HSV-2 infection (I$ million)
Global	53	30	15	6	2
African	6	0.0	2	3	2
Americas	22	18	4	0.2	0.0
Eastern Mediterranean	3	1.4	0.8	1.1	0.1
Europe	10	8	2	0.2	0.0
South-East Asia^b	1.1	-	0.1	1.0	0.0
Western Pacific^c	10	3	6	0.6	-
	Neonatal herpes due to a maternal HSV-1 infection (I$ million)
Global	61	41	18	2	0.1
African	0.0	0.0	0.0	0.0	0.0
Americas	36	28	8	0.3	0.0
Eastern Mediterranean	1.5	0.5	0.4	0.5	0.1
Europe	13	9	3	0.3	0.0
South-East Asia^b	0.1	-	0.0	0.1	0.0
Western Pacific^c	11	3	7	0.7	-
	HIV attributable to HSV-2 (I$ million)
Global	352	92	199	47	14
African	219	0.0	168	38	14
Americas	78	56	21	0.2	0.2
Eastern Mediterranean	0.8	0.2	0.3	0.3	0.0
Europe	41	34	4	3	0.0
South-East Asia^b	6	-	0.5	5	0.0
Western Pacific^c	8	2	5	0.9	-

Totals may vary due to rounding. The numbers are given to the nearest integer from model estimates
^aNo estimates were generated for the African region for HSV-1 due to lack of information on disease burden
^bNo countries within the South-East Asia region were classified as high income
^cNo countries within the Western Pacific region were classified as low income

ISSN: 2731-913X