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Table 2 Baseline characteristics, cascade of care and time to TB treatment commencement and completion among participants who completed the telephonic survey, stratified by TB symptom status at baseline

From: Subclinical tuberculosis linkage to care and completion of treatment following community-based screening in rural South Africa

 

Microbiologically-confirmed TB

Radiologically-suggested TB

Characteristic

Asymptomatic,

N = 103a

Symptomatic,

N = 19a

p-value

Asymptomatic,

N = 122a

Symptomatic,

N = 31a

p-value

I. Baseline Characteristics

Age group

  

0.33

  

0.0393

 < 25

13 (13%)

1 (5%)

 

7 (6%)

1 (3%)

 

 25–44

38 (37%)

4 (21%)

 

26 (21%)

1 (3%)

 

 45–64

31 (30%)

8 (42%)

 

67 (55%)

19 (61%)

 

 > 65

21 (20%)

6 (32%)

 

22 (18%)

10 (32%)

 

Sex

  

0.72

  

0.72

 Male

48 (47%)

8 (42%)

 

67 (55%)

16 (52%)

 

 Female

55 (53%)

11 (58%)

 

55 (45%)

15 (48%)

 

HIV ELISA

  

0.92

  

0.112

 Negative

56 (54%)

10 (53%)

 

55 (45%)

19 (61%)

 

 Positive

47 (46%)

9 (47%)

 

67 (55%)

12 (39%)

 

CAD4TBv5 Score

64 (45, 77)

60 (55, 71)

 > 0.94

86 (70, 95)

85 (74, 98)

0.64

Residency location

  

0.43

  

0.103

 Rural

62 (60%)

12 (63%)

 

71 (58%)

24 (77%)

 

 Peri-urban

39 (38%)

6 (32%)

 

42 (34%)

7 (23%)

 

 Urban

2 (2%)

1 (5%)

 

9 (7%)

0 (0%)

 

Socioeconomic status

  

0.53

  

0.33

 Lowest

16 (16%)

2 (11%)

 

15 (12%)

6 (19%)

 

 Low

29 (28%)

10 (53%)

 

33 (27%)

11 (35%)

 

 Middle

26 (25%)

3 (16%)

 

28 (23%)

3 (10%)

 

 High

13 (13%)

2 (11%)

 

22 (18%)

7 (23%)

 

 Highest

15 (15%)

2 (11%)

 

18 (15%)

3 (10%)

 

 Unknown

4 (4%)

0 (0%)

 

6 (5%)

1 (3%)

 

II. Cascade of care

Attended clinic/hospital (self-reported)

101 (98%)

18 (95%)

0.43

90 (74%)

24 (77%)

0.72

 Facility attended

  

0.53

  

0.63

   Clinic

98 (97%)

17 (94%)

 

22 (24%)

4 (17%)

 

   Hospital

3 (3%)

1 (6%)

 

68 (76%)

20 (83%)

 

Started TB treatment (self-reported)

98 (95%)

17 (89%)

0.33

19 (16%)

5 (16%)

 > 0.93

Started TB treatment (Tier.net)

72 (70%)

16 (84%)

0.23

11 (9%)

4 (13%)

0.53

Completed TB treatment (self-reported)

96 (93%)

17 (89%)

0.33

17 (14%)

5 (16%)

0.83

III. Time to starting and completing TB treatment

Time to starting TB treatment (days, self-reported)

22 (14, 30)

20 (10, 22)

0.124

41 (31, 72)

43 (42, 73)

0.74

Time to starting TB treatment (days, Tier.net)

9 (8, 24)

26 (11, 29)

0.144

45 (34, 58)

66 (55, 79)

0.24

Percentage of individuals starting TB treatment (by self-report) within:

  

0.63

  

 > 0.93

 0–30 days

72 (73%)

14 (82%)

 

4 (21%)

1 (20%)

 

 31–60 days

16 (16%)

1 (6%)

 

6 (32%)

2 (40%)

 

 61–90 days

4 (4%)

1 (6%)

 

3 (16%)

1 (20%)

 

 More than 90 days

4 (4%)

0 (0%)

 

4 (21%)

1 (20%)

 

 Unknown

2 (2%)

1 (6%)

 

2 (11%)

0 (0%)

 

Time to completing TB treatment (days, self-report)

208 (202, 218)

205 (202, 216)

0.34

259 (224, 292)

255 (225, 257)

0.74

  1. aMedian (IQR); n (%)
  2. 2Statistical test used: Pearson’s Chi-squared test
  3. 3Statistical test used: Fisher’s exact test
  4. 4Statistical test used: Wilcoxon rank sum test