Table 1 Study outcomes mapped using the RE-AIM framework
Construct | Definition | Outcomes | Measures | Data source | Frequency |
|---|---|---|---|---|---|
Reach | Individual-level measure of participation | Proportion and characteristics of women counselled on HIV prevention and initiated on PrEP | Number of patients served Proportion starting on PrEP by pregnancy vs. postpartum/breastfeeding | Clinic routine data: Counsellor’s HIV testing register, clinic attendance record, PrEP register | Completed by counsellor and nurses and captured weekly by research assistant |
Effectiveness | Achievement of programme goals and objectives | PrEP continuation rate | Proportion of women who continue PrEP at up to 3 months by pregnant vs. postpartum/breastfeeding PrEP cascade from testing, initiation to continuation | PrEP Department of Health register PrEP register | PrEP register completed by providers during the refill visit. Captured weekly by research assistant |
Adoption | Assessment of the delivery setting | Proportion of staff who adhered to training and PrEP delivery by staff cadre and setting | Proportion of staff and providers who participated in the training and intervention Barriers and facilitators to adoption (to be reported in qualitative analysis in subsequent report) | Pre- and post-training test PrEP mentoring assessment checklist — completed by the study nurse/counsellor | Before and after training During mentorship (over 6 months, following training) |
Implementation | Extent to which the intervention was delivered | Adherence to the planned intervention | Trends in patient counselling and screening for PrEP | Implementation log and PrEP data collected from clinic and staff | Monthly data reviewed (spanning from training to end of mentorship) |
Maintenance | Institutionalisation of the programme | Adherence to the planned integration beyond the study period | Current data from clinic on PrEP counselling and provision (following intervention) | Clinic routine data: Counsellor’s HIV testing book, PMTCT register, PrEP registers, and review of electronic data | PrEP initiation and continuation data among PBFW by clinic 3 months post end of intervention |